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The effects begin to be noticed after about 20 minutes. You start feeling relaxed, something sleepy, even. Depending on how much you have taken, you may suffer from perception alterations and perhaps blurred vision. The effects reach their peak after one hour. With high doses, there may be coordination problems or even memory gaps may occur. In any case, even if you are still aware, you will remember absolutely nothing.
If you have ever taken Xanax, you will already know these symptoms . What you may not know is what exactly happens in the brain under the influence of this drug.
Xanax is the brand name of alprazolam, a drug belonging to the benzodiazepine group, which is usually prescribed to treat anxiety. As with all medications taken by mouth, the body absorbs it through the stomach, through the mucous membrane and into the liver. From there, it passes into the bloodstream and reaches the brain, where it crosses the blood-brain barrier, a membrane that serves as a filter for dangerous substances. Benzodiazepines, like many other drugs, are able to cross this barrier.
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And it is in the brain where things get interesting. Benzodiazepines act on parts of the brain called GABA-A receptors, which would be a kind of switch, each of which has a different effect. GABA-A receptors are responsible for producing a sedative effect and are activated by neurotransmitters, chemicals that carry messages through the brain. Specifically, it is the GABA neurotransmitter that activates the GABA-A receptors. Val Curran, professor of Psychopharmacology at the UCL, describes the GABA neurotransmitter as “the brakes of the brain, which calms everything.”
“If you take Xanax for recreational purposes, what you will get is a tremendous sedative effect. And as in your case you have no chemical imbalance, there will be everything”
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